A lower duodenal immune response is associated with an increase of insulin resistance in patients with morbid obesity

Objective The intestinal immune response could play an important role in obesity-related comorbidities. We aim to study the profile of duodenal cytokines and chemokines in patients with morbid obesity (MO), its relation with insulin resistance (IR) and the intake of metformin, and with the evolution...

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Veröffentlicht in:	INTERNATIONAL JOURNAL OF OBESITY 2020-02, Vol.44 (2), p.340-352
Hauptverfasser:	Ho-Plagaro, Ailec, Santiago-Fernandez, Concepción, García-Serrano, Sara, Rodriguez, Cristina, Garrido-Sanchez, Lourdes, Escamilla, Alejandro, Gonzalo, Montserrat, Montiel-Casado, Custodia, Alcaín-Martínez, Guillermo, Garcia-Muñoz, Beatriz, Ruiz-Santana, Natalia, Vázquez-Pedreño, Luis, Garcia-Fuentes, Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	13/21 631/443/319/1642/137/773 692/163/2743/393 82/80 Adult Analysis Body mass index Body size Care and treatment Chemokines Comorbidity Cytokines Cytokines - analysis Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Duodenum - chemistry Duodenum - cytology Duodenum - immunology Endocrinology & Metabolism Epidemiology Evolution Female Gastrectomy Health Promotion and Disease Prevention Helper cells Humans Hypoglycemic agents Hypoglycemic Agents - therapeutic use Immune response Immune system Insulin Insulin Resistance Interleukin 2 Interleukin 22 Interleukin 4 Internal Medicine Intestine Life Sciences & Biomedicine Lymphocytes Lymphocytes T Macrophages Male Medicine Medicine & Public Health Metabolic Diseases Metformin Metformin - therapeutic use Middle Aged Nutrition & Dietetics Obesity Obesity, Morbid - complications Obesity, Morbid - epidemiology Obesity, Morbid - immunology Obesity, Morbid - metabolism Public Health Research design Science & Technology Type 2 diabetes
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