Exclusive dependence of IL-10R[alpha] signalling on intestinal microbiota homeostasis and control of whipworm infection

The whipworm Trichuris trichiura is a soil-transmitted helminth that dwells in the epithelium of the caecum and proximal colon of their hosts causing the human disease, trichuriasis. Trichuriasis is characterized by colitis attributed to the inflammatory response elicited by the parasite while tunne...

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Veröffentlicht in:	PLoS Pathogens 2019, Vol.15 (1)
Hauptverfasser:	Duque-Correa, María A, Karp, Natasha A, McCarthy, Catherine, Forman, Simon, Goulding, David, Sankaranarayanan, Geetha, Jenkins, Timothy P, Reid, Adam J, Cambridge, Emma L, Ballesteros Reviriego, Carmen, Müller, Werner, Cantacessi, Cinzia, Dougan, Gordon, Grencis, Richard K, Berriman, Matthew
Format:	Report
Sprache:	eng
Schlagworte:	B cells Bacteria Colitis Epithelium Genetic aspects Health aspects Homeostasis Human whipworm Infection control Inflammation Interleukin-10 Liver diseases Microbiota (Symbiotic organisms) Pathogenic microorganisms Physiological aspects Roundworm infections
Online-Zugang:	Volltext
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