DNA-binding sequence specificity of DUX4

Background Misexpression of the double homeodomain transcription factor DUX4 results in facioscapulohumeral muscular dystrophy (FSHD). A DNA-binding consensus with two tandem TAAT motifs based on chromatin IP peaks has been discovered; however, the consensus has multiple variations (flavors) of unkn...

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Veröffentlicht in:Skeletal Muscle 2016, Vol.6 (8)
Hauptverfasser: Zhang, Yu, Lee, John K, Toso, Erik A, Lee, Joslynn S, Choi, Si Ho, Slattery, Matthew, Aihara, Hideki, Kyba, Michael
Format: Report
Sprache:eng
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