Rheological behavior and microbiological studies of Carbopol® hydrogels
Rheological and microbiological studies were performed for hydrogels prepared with different types of crosslinked polyacrylate polymers (Carbopol® 940, 980 and Ultrez® 10). All hydrogels exhibited typical viscoelastic properties, with no Newtonian flow regimen. Linearizing viscosity profiles, excell...
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| Veröffentlicht in: | Studia Universitatis Babeș-Bolyai. Chemia 2015-03, p.177 |
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| creator | Sipos, Emese Szabo, Zoltan-Istvan Lorinczi, Lilla Ciurba, Adriana |
| description | Rheological and microbiological studies were performed for hydrogels prepared with different types of crosslinked polyacrylate polymers (Carbopol® 940, 980 and Ultrez® 10). All hydrogels exhibited typical viscoelastic properties, with no Newtonian flow regimen. Linearizing viscosity profiles, excellent correlations were obtained between logarithmic values of viscosity and shear rate. The study also revealed that Carbopol® 980 and Ultrez® 10 based hydrogels showed higher viscosity than the Carbopol® 940 based. Microbiological studies were performed in order to find a suitable preservative for the prepared hydrogels. Both the diffusion based method and challenge test indicated that phenylmercuric borate was the most effective preservative, regardless of the microorganism tested and can be suitable for preventing antimicrobial growth in the prepared hydrogels. Keywords: Carbopol®, hydrogel, pseudoplastic, challenge test |
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All hydrogels exhibited typical viscoelastic properties, with no Newtonian flow regimen. Linearizing viscosity profiles, excellent correlations were obtained between logarithmic values of viscosity and shear rate. The study also revealed that Carbopol® 980 and Ultrez® 10 based hydrogels showed higher viscosity than the Carbopol® 940 based. Microbiological studies were performed in order to find a suitable preservative for the prepared hydrogels. Both the diffusion based method and challenge test indicated that phenylmercuric borate was the most effective preservative, regardless of the microorganism tested and can be suitable for preventing antimicrobial growth in the prepared hydrogels. Keywords: Carbopol®, hydrogel, pseudoplastic, challenge test</description><identifier>ISSN: 1224-7154</identifier><language>eng</language><publisher>Universitatea Babes-Bolyai. Chemia</publisher><subject>Measurement ; Mechanical properties ; Polymer networks ; Polymers ; Rheology ; Viscoelasticity</subject><ispartof>Studia Universitatis Babeș-Bolyai. Chemia, 2015-03, p.177</ispartof><rights>COPYRIGHT 2015 Universitatea Babes-Bolyai. Chemia</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Sipos, Emese</creatorcontrib><creatorcontrib>Szabo, Zoltan-Istvan</creatorcontrib><creatorcontrib>Lorinczi, Lilla</creatorcontrib><creatorcontrib>Ciurba, Adriana</creatorcontrib><title>Rheological behavior and microbiological studies of Carbopol® hydrogels</title><title>Studia Universitatis Babeș-Bolyai. Chemia</title><description>Rheological and microbiological studies were performed for hydrogels prepared with different types of crosslinked polyacrylate polymers (Carbopol® 940, 980 and Ultrez® 10). All hydrogels exhibited typical viscoelastic properties, with no Newtonian flow regimen. Linearizing viscosity profiles, excellent correlations were obtained between logarithmic values of viscosity and shear rate. The study also revealed that Carbopol® 980 and Ultrez® 10 based hydrogels showed higher viscosity than the Carbopol® 940 based. Microbiological studies were performed in order to find a suitable preservative for the prepared hydrogels. Both the diffusion based method and challenge test indicated that phenylmercuric borate was the most effective preservative, regardless of the microorganism tested and can be suitable for preventing antimicrobial growth in the prepared hydrogels. 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Chemia</general><scope/></search><sort><creationdate>20150301</creationdate><title>Rheological behavior and microbiological studies of Carbopol® hydrogels</title><author>Sipos, Emese ; Szabo, Zoltan-Istvan ; Lorinczi, Lilla ; Ciurba, Adriana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g194t-8c534721a4eee9d81ee7c947a88ee045a9e9a95157ed2d5f9949c54b046a384e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Measurement</topic><topic>Mechanical properties</topic><topic>Polymer networks</topic><topic>Polymers</topic><topic>Rheology</topic><topic>Viscoelasticity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sipos, Emese</creatorcontrib><creatorcontrib>Szabo, Zoltan-Istvan</creatorcontrib><creatorcontrib>Lorinczi, Lilla</creatorcontrib><creatorcontrib>Ciurba, Adriana</creatorcontrib><jtitle>Studia Universitatis Babeș-Bolyai. 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The study also revealed that Carbopol® 980 and Ultrez® 10 based hydrogels showed higher viscosity than the Carbopol® 940 based. Microbiological studies were performed in order to find a suitable preservative for the prepared hydrogels. Both the diffusion based method and challenge test indicated that phenylmercuric borate was the most effective preservative, regardless of the microorganism tested and can be suitable for preventing antimicrobial growth in the prepared hydrogels. Keywords: Carbopol®, hydrogel, pseudoplastic, challenge test</abstract><pub>Universitatea Babes-Bolyai. Chemia</pub></addata></record> |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals |
| subjects | Measurement Mechanical properties Polymer networks Polymers Rheology Viscoelasticity |
| title | Rheological behavior and microbiological studies of Carbopol® hydrogels |
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