Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations

Identification of polymorphisms that influence pemetrexed tolerability could lead to individualised treatment regimens and improve quality of life. Twenty-eight polymorphisms within eleven candidate genes were genotyped using the Illumina Human Exome v1.1 BeadChip and tested for their association wi...

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Veröffentlicht in:	The Pharmacogenomics Journal 2014, Vol.14 (5), p.411
Hauptverfasser:	Corrigan, A, Walker, J.L, Wickramasinghe, S, Hernandez, M.A, Newhouse, S.J, Folarin, A.A, Lewis, C.M, Sanderson, J.D, Spicer, J, Marinaki, A.M
Format:	Report
Sprache:	eng
Schlagworte:	Complications and side effects Drug metabolism Drug therapy Genetic aspects Genetic polymorphisms Lung cancer Pemetrexed Properties
Online-Zugang:	Volltext
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