Synthesis of New Isolated and Fused Tri- and Tetracyclic Pyridine Derivatives

A number of functionalized pyridine derivatives in which the pyridine ring is linked to triazole, thiadiazole, thiazole, and tetrazole moieties were synthesized by cyclization with carbon disulfide, phenylisothiocyanate, and sodium azide. Benzylation of the synthesized tetrazolylmethylpyridone deriv...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2013-03, Vol.48 (12), p.1853-1862
Hauptverfasser: Essawy, F.A. El, Sayed, W.A. El, Etrawy, A. Sh. El, Bayaa, M.N. El
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container_issue 12
container_start_page 1853
container_title Chemistry of heterocyclic compounds (New York, N.Y. 1965)
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creator Essawy, F.A. El
Sayed, W.A. El
Etrawy, A. Sh. El
Bayaa, M.N. El
description A number of functionalized pyridine derivatives in which the pyridine ring is linked to triazole, thiadiazole, thiazole, and tetrazole moieties were synthesized by cyclization with carbon disulfide, phenylisothiocyanate, and sodium azide. Benzylation of the synthesized tetrazolylmethylpyridone derivative afforded the N (1)-benzylated product; its crystal structure is reported. The substituted fused tetracyclic pyridofuropyrimidine was synthesized by sequential reactions starting from the 2-pyridone derivative.
doi_str_mv 10.1007/s10593-013-1219-z
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subjects Alkaloids
Chemistry
Chemistry and Materials Science
Organic Chemistry
Pharmacy
Pyridine
Triazoles
title Synthesis of New Isolated and Fused Tri- and Tetracyclic Pyridine Derivatives
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