Development of liquid chromatographic methods for determination of quinocetone and its main metabolites in edible tissues of swine and chicken

Quinocetone (QCT), a new antimicrobial growth promotant of quinoxalines, can effectively improve the growth and feed efficiency of food animals with more safety than is provided by olaquindox and carbadox. To clarify its metabolism and residue levels in animals, a liquid chromatographic method with...

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Veröffentlicht in:	Journal of AOAC International 2005-03, Vol.88 (2), p.472-478
Hauptverfasser:	Huang, L, Xiao, A, Fan, S, Yin, J, Chen, P, Liu, D, Qiu, Y, Wang, Y, Yuan, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	3-methylquinoxaline-2-carboxylic acid Animal productions Animals Anti-Infective Agents - analysis Anti-Infective Agents - pharmacokinetics antimicrobial agents backfat Biological and medical sciences Biotransformation Calibration Chickens Chromatography, Liquid Citric acid desoxyquinocetone (DQCT) detection drug residues Drug Residues - analysis Esters Fundamental and applied biological sciences. Psychology growth promotion growth regulators Hydrolysis Indicators and Reagents kidneys as food liver Meat - analysis Metabolites Methods new drugs new methods pharmacokinetics Physiological aspects quantitative analysis quinocetone (ACT) quinoxalines Quinoxalines - analysis Quinoxalines - pharmacokinetics Reference Standards skeletal muscle Solubility Solutions Spectrophotometry, Ultraviolet structure-activity relationships Swine synthetic products Terrestrial animal productions Vertebrates veterinary drugs
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