Mitogen-activated protein kinases and NF[kappa]B are involved in SP-A-enhanced responses of macrophages to mycobacteria

Background Surfactant protein A (SP-A) is a C-type lectin involved in surfactant homeostasis as well as host defense in the lung. We have recently demonstrated that SP-A enhances the killing of bacillus Calmette-Guerin (BCG) by rat macrophages through a nitric oxide-dependent pathway. In the current...

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Veröffentlicht in:	Respiratory research 2009-07, Vol.10, p.60
Hauptverfasser:	Lopez, Joseph P, Vigerust, David J, Shepherd, Virginia L
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA binding proteins Health aspects Lectins Macrophages Physiological aspects Protein kinases
Online-Zugang:	Volltext
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