Impaired antibody response causes persistence of prototypic T cell-contained virus

CD8 T cells are recognized key players in control of persistent virus infections, but increasing evidence suggests that assistance from other immune mediators is also needed. Here, we investigated whether specific antibody responses contribute to control of lymphocytic choriomeningitis virus (LCMV),...

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Veröffentlicht in:	PLoS Biology 2009, Vol.7 (4), p.789
Hauptverfasser:	Bergthaler, Andreas, Flatz, Lukas, Verschoor, Admar, Hegazy, Ahmed N, Holdener, Ma, Fink, Katja, Eschli, Bruno, Merkler, Doron, Sommerstein, Rami, Horvath, Edit, Fernandez, Marylise, Fitsche, Andre, Senn, Beatrice M, Verbeek, J. Sjef, Odermatt, Bernhard, Siegrist, Claire-Anne, Pinschewer, Daniel D
Format:	Report
Sprache:	eng
Schlagworte:	CD8 lymphocytes Development and progression Immune response Patient outcomes Physiological aspects Viremia
Online-Zugang:	Volltext
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