Multidrug resistant Escherichia coli isolates of poultry origin in Abeokuta, South Western Nigeria / Multipla rezistencija izolata bakterije Escherichia coli podrijetlom iz peradi iz Abeokute u jugozapadnoj Nigeriji

Thirty nine Escherichia coli (E. coli) isolated from septicaemic clinical cases between October 2005 and March 2006 from eleven poultry farms in Abeokuta, South West Nigeria were tested for their in vitro antimicrobial drug sensitivity pattern. The E. coli were isolated from two hundred and fifty samples comprising of intestine, kidneys, lungs, hearts, ovary, spleen and colo-rectum from diseased chickens (mostly commercial layers) submitted for post-mortem examination. Eight of the poultry farms studied disclosed that they had used between 3 to 7 different antimicrobial agents either for treatment, prophylaxis or as growth promoters within the studied period. The result indicated that the 39 E. coli isolates showed nineteen different multidrug-resistant patterns to Nitrofurantoin (100 µg), Cefuroxime (20 µg), Norfloxacin (10 µg), Cotrimoxazole (50 µg), Ciprofloxacin (5 µg), Nalidicic acid (30 µg), Chloramphenicol (10 µg), Ampicillin (10 µg, 25 µg), Ofloxacin (5 µg), Penicillin G (5 i.u), Amoxylin (20 µg), and Cloxacilin (5 µg, 10 µg) discs that were tested. Key words: Escherichia coli, multidrug resistant, poultry Ukupno je 39 izolata bakterije Escherichia coli bilo izdvojeno iz peradi sa septikemijom od listopada 2005. do ozujka 2006. s 11 farmi u Abeokuti u jugozapadnoj Nigeriji. Svi su izolati bili pretrazeni na osjetljivost prema antimikrobnim tvarima. E. coli bila je izdvojena iz 250 uzoraka tkiva razlicitih organa: crijeva, bubrega, pluca, srca, jajnika, slezene i izlaznoga crijeva (rektuma) oboljelih pilica dostavljenih na postmortalnu pretragu. Na osam od 11 pretrazenih farmi bilo je rabljeno od tri do sedam razlicitih antimikrobnih tvari za lijecenje, profilaksu ili pak kao promotori rasta. Ustanovljeno je da je 39 izolata E. coli pokazivalo 19 razlicitih nacina visestruke otpomostiprema nitrofurantoinu (100 µg), cefuroksimu (20 µg), norfloksacinu (10 µg) kotrimoksazolu (50 µg), ciprofloksacinu (5 µg), nalidiksicnoj kiselini (30 µg), kloramfenikolu (10 µg), ampicilinu (10 µg, 25 µg), ofloksacinu (5 µg), penicilinu G (5 i.j.), amoksicilinu (20 µg) i kloksacilinu (5 µg). Kljucne rijeci: Escherichia coli, mnogostruka otpomost perad