Gadd45β is important for perpetuating cognate and inflammatory signals in T cells

Gadd45β (growth arrest and DNA damage–inducible, β) is involved in cell cycle arrest, apoptosis, signal transduction and cell survival. In T cells, Gadd45b was rapidly induced by T cell receptor (TCR) and inflammatory signals. Deficiency of Gadd45β in CD4 + T cells impaired their responses to TCR st...

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Veröffentlicht in:	Nature immunology 2004-01, Vol.5 (1), p.38-44
Hauptverfasser:	Flavell, Richard A, Lu, Binfeng, Ferrandino, Anthony F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Immunology Infectious Diseases
Online-Zugang:	Volltext
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