Maintenance of Hepatic Nuclear Factor 6 in Postnatal Islets Impairs Terminal Differentiation and Function of β-Cells

Maintenance of Hepatic Nuclear Factor 6 in Postnatal Islets Impairs Terminal Differentiation and Function of β-Cells Elizabeth Tweedie 1 2 , Isabella Artner 2 , Laura Crawford 1 2 , Greg Poffenberger 1 , Bernard Thorens 3 , Roland Stein 2 , Alvin C. Powers 1 2 4 and Maureen Gannon 1 2 1 Department o...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2006-12, Vol.55 (12), p.3264-3270
Hauptverfasser:	TWEEDIE, Elizabeth, ARTNER, Isabella, CRAWFORD, Laura, POFFENBERGER, Greg, THORENS, Bernard, STEIN, Roland, POWERS, Alvin C, GANNON, Maureen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Care and treatment Cell Differentiation Diabetes Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Gene Expression Regulation, Developmental Glucose - metabolism Glucose - pharmacology Glucose Transporter Type 2 - genetics Health aspects Hepatocyte Nuclear Factor 6 - genetics Homeodomain Proteins - genetics Homeostasis Insulin - metabolism Insulin Secretion Insulin-Secreting Cells - cytology Insulin-Secreting Cells - metabolism Insulin-Secreting Cells - physiology Islets of Langerhans - physiology Medical sciences Mice Mice, Transgenic Pancreatic beta cells Trans-Activators - genetics
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