The exquisite specificity of human protein arginine methyltransferase 7

Mammalian protein arginine methyltransferase 7 (PRMT7) has been shown to target substrates with motifs containing two arginine residues separated by one other residue (RXR motifs). In particular, the repression domain of human histone H2B (29-RKRSR-33) has been a key substrate in determining PRMT7 a...

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Veröffentlicht in:	PloS one 2023-05, Vol.18 (5), p.e0285812
Hauptverfasser:	Bondoc, Timothy J, Lowe, Troy L, Clarke, Steven G
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Arginine Evaluation Methylation Peptides Post-translational modification Properties Proteins Transferases
Online-Zugang:	Volltext
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