Transcriptomic Analysis Reveals that Activating Transcription Factor 3/c-Jun/Lgals3 Axis Is Associated with Central Diabetes Insipidus after Hypothalamic Injury

Background: Hypothalamic injury causes several complicated neuroendocrine-associated disorders, such as water-electrolyte imbalance, obesity, and hypopituitarism. Among these, central diabetes insipidus (CDI), characterized by polyuria, polydipsia, low urine specific gravity, and deficiency of argin...

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Veröffentlicht in:	Neuroendocrinology 2022-08, Vol.112 (9), p.874-893
Hauptverfasser:	Zhou, Mingfeng, Ou, Yichao, Wu, Guangsen, Li, Kai, Peng, Junjie, Wang, Xingqin, Che, Mengjie, Gong, Haodong, Niu, Peirong, Liu, Yawei, Feng, Zhanpeng, Qi, Songtao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal behavior Brain Diabetes insipidus Electrolytes Ethylenediaminetetraacetic acid Neurons Physiological aspects Research Article RNA RNA sequencing Vasopressin
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