Pulmonary insults exacerbate susceptibility to oral Listeria monocytogenes infection through the production of IL-10 by NK cells

Most individuals who consume foods contaminated with the bacterial pathogen Listeria monocytogenes (Lm) develop mild symptoms, while others are susceptible to life-threatening systemic infections (listeriosis). Although it is known that the risk of severe disease is increased in certain human popula...

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Veröffentlicht in:	PLoS pathogens 2021-04, Vol.17 (4), p.e1009531, Article 1009531
Hauptverfasser:	Bortell, Nikki, Aguilera, Elizabeth R., Lenz, Laurel L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Biology and Life Sciences Complications and side effects COVID-19 Cytokines Development and progression Disease Progression Disease Susceptibility Exposure Female Food Food contamination Gastroenteritis Health aspects Immune response Inflammation Influenza Interleukin 10 Interleukin-10 - metabolism Killer cells Killer Cells, Natural - metabolism Killer Cells, Natural - physiology Life Sciences & Biomedicine Lipopolysaccharides Listeria Listeria monocytogenes Listeria monocytogenes - immunology Listeria monocytogenes - pathogenicity Listeriosis Listeriosis - complications Listeriosis - immunology Listeriosis - pathology Lung diseases Lungs Lymph nodes Lymphatic system Male Medicine and Health Sciences Mice Mice, Inbred C57BL Mice, Transgenic Microbiology Morbidity Mortality Mouth diseases Mouth Diseases - complications Mouth Diseases - immunology Mouth Diseases - microbiology Mouth Diseases - pathology Natural killer cells Oral infection Oral mucosa Parasitology Pathogens Phagocytes Pneumonia - complications Pneumonia - etiology Pneumonia - immunology Pneumonia - pathology Risk factors Science & Technology Streptococcus infections Tissues Tuberculosis Virology
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