Exploring Physical and Chemical Factors Influencing the Properties of Recombinant Prion Protein and the Real-Time Quaking-Induced Conversion

Real-time quaking-induced conversion (RT-QuIC), a highly specific and sensitive assay able to detect low levels of the disease-inducing isoform of the prion protein (PrP.sup.d) in brain tissue biopsies and cerebral spinal fluid, has great potential to become a method for diagnosing prion disease ant...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e84812
Hauptverfasser:	Cheng, Keding, Sloan, Angela, Avery, Kristen M, Coulthart, Michael, Carpenter, Michael, Knox, J. David
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Creutzfeldt-Jakob disease Hamsters Prions (Proteins)
Online-Zugang:	Volltext
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