Cytoplasmic Location of [alpha]1A Voltage-Gated Calcium Channel C-Terminal Fragment

The human [alpha].sub.1A voltage-dependent calcium channel (Ca.sub.v 2.1) is a pore-forming essential subunit embedded in the plasma membrane. Its cytoplasmic carboxyl(C)-tail contains a small poly-glutamine (Q) tract, whose length is normally 4~19 Q, but when expanded up to 20~33Q, the tract causes...

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Veröffentlicht in:	PloS one 2013-03, Vol.8 (3), p.e50121
Hauptverfasser:	Takahashi, Makoto, Obayashi, Masato, Ishiguro, Taro, Sato, Nozomu, Niimi, Yusuke, Ozaki, Kokoro, Mogushi, Kaoru, Mahmut, Yasen, Tanaka, Hiroshi, Tsuruta, Fuminori, Dolmetsch, Ricardo, Yamada, Mitsunori, Takahashi, Hitoshi, Kato, Takeo, Mori, Osamu, Eishi, Yoshinobu, Mizusawa, Hidehiro, Ishikawa, Kinya
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Brain Calcium channels Cell death Glutamine Nervous system diseases Protein binding
Online-Zugang:	Volltext
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