Congenital Hepatic Fibrosis in the Franches-Montagnes Horse Is Associated with the Polycystic Kidney and Hepatic Disease 1

Congenital hepatic fibrosis has been described as a lethal disease with monogenic autosomal recessive inheritance in the Swiss Franches-Montagnes horse breed. We performed a genome-wide association study with 5 cases and 12 controls and detected an association on chromosome 20. Subsequent homozygosi...

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Veröffentlicht in:	PloS one 2014-10, Vol.9 (10)
Hauptverfasser:	Drögemüller, Michaela, Jagannathan, Vidhya, Welle, Monika M, Graubner, Claudia, Straub, Reto, Gerber, Vinzenz, Burger, Dominik, Signer-Hasler, Heidi, Poncet, Pierre-André, Klopfenstein, Stéphane, von Niederhäusern, Ruedi, Tetens, Jens, Thaller, Georg, Rieder, Stefan, Drögemüller, Cord, Leeb, Tosso
Format:	Artikel
Sprache:	eng
Schlagworte:	Fibrosis Genetic disorders Genomes Genomics Kidney diseases Liver
Online-Zugang:	Volltext
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