Evaluation of Novel Large Cut-Off Ultrafiltration Membranes for Adenovirus Serotype 5

The purification of virus particles and viral vectors for vaccine and gene therapy applications is gaining increasing importance in order to deliver a fast, efficient, and reliable production process. Ultrafiltration (UF) is a widely employed unit operation in bioprocessing and its use is present in...

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Veröffentlicht in:	PloS one 2014-12, Vol.9 (12)
Hauptverfasser:	Nestola, Piergiuseppe, Martins, Duarte L, Peixoto, Cristina, Roederstein, Susanne, Schleuss, Tobias, Alves, Paula M, Mota, José P. B, Carrondo, Manuel J. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Cellulose Gene therapy Genetic vectors Permeability Vaccines
Online-Zugang:	Volltext
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