Germ-line mutations in epidermal growth factor receptor

Background A subset of lung cancer patients harbour EGFR somatic mutations in their tumours and are candidates for treatment with EGFR tyrosine kinase inhibitors. In a few cases EGFR mutations have also been found in the germ line, suggesting a role in lung carcinogenesis. Objetives of this study we...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	BMC cancer 2011-05, Vol.11, p.172
Hauptverfasser:	Santamaría, Iñigo, Freije, Jose M, Iglesias, Fernando, Balbín, Milagros, Astudillo, Aurora, Centeno, Irene, Osorio, Fernando G, Menéndez, Primitiva, Blay, Pilar, Pitiot, Ana S, Tardón, Adonina, González-Arriaga, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene mutations Genetic aspects Health aspects Lung cancer Risk factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!