[Beta]-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human [Beta]-defensins are also chemotactic for immature dendritic cells and memory T cells. Human [Beta]-defensin was selectively chemotactic for cells stably transfected to express...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1999-10, Vol.286 (5439), p.525-525
Hauptverfasser: Yang, D, Chertov, O, Bykovskaia, S. N, Chen, Q, Buffo, M. J, Shogan, J, Anderson, M, Schroder, J. M, Wang, J. M, Howard, O. M. Z, Oppenheim, J. J
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Sprache:eng
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