Design, Synthesis, Pharmacological Evaluation of Quinazolin-4

Background: In response to the urgent need for continuous discovery of new anti-proliferative agents, a new series of quinazoline compounds 5a-r was prepared. Methods: As a reference, four cancer cell lines--HCT116, HePG2, Hela, and MCF-7--and sorafenib (SOR) were used to assess the novel motifs...

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Veröffentlicht in:	Drug design, development and therapy development and therapy, 2024-11, Vol.18, p.5109
Hauptverfasser:	Mohamed, Ahmed A.B, Hussein, Shaimaa, Hafez, Hani M, Alsahli, Tariq G, Tawfik, Samar S, El-Shafey, Hamed W, Hamdi, Abdelrahman, Al-Sanea, Mohammad M, Ewes, Wafaa A, Elgazar, Abdullah A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimitotic agents Antineoplastic agents Cancer Care and treatment Urea Vascular endothelial growth factor
Online-Zugang:	Volltext
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