Ten-year longitudinal molecular epidemiology study of Escherichia coli and Klebsiella species bloodstream infections in Oxfordshire, UK

Background The incidence of Gram-negative bloodstream infections (BSIs), predominantly caused by Escherichia coli and Klebsiella species, continues to increase; however, the causes of this are unclear and effective interventions are therefore hard to design. Methods In this study, we sequenced 3468...

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Veröffentlicht in:	Genome medicine 2021-09, Vol.13 (1), p.144-144, Article 144
Hauptverfasser:	Lipworth, Samuel, Vihta, Karina-Doris, Chau, Kevin, Barker, Leanne, George, Sophie, Kavanagh, James, Davies, Timothy, Vaughan, Alison, Andersson, Monique, Jeffery, Katie, Oakley, Sarah, Morgan, Marcus, Hopkins, Susan, Peto, Timothy E. A., Crook, Derrick W., Walker, Ann Sarah, Stoesser, Nicole
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibiotics Antimicrobial agents Antimicrobial resistance Bacteraemia Bacteremia - epidemiology Cloning Comparative analysis Discriminant analysis Drug resistance Drug resistance in microorganisms Drug Resistance, Multiple, Bacterial E coli Epidemiology Escherichia coli Escherichia coli - genetics Escherichia coli Infections - epidemiology Gene transfer Genes Genetic factors Genetics & Heredity Genomes Genomics Geographical distribution Gram-negative bloodstream infections Health aspects Horizontal transfer Humans Incidence Infection Infections Insertion sequences Klebsiella Klebsiella - genetics Klebsiella Infections - epidemiology Klebsiella pneumoniae - genetics Laboratories Life Sciences & Biomedicine Longitudinal Studies Molecular Epidemiology Phylogenetics Plasmids Population Population structure Public health Science & Technology Sepsis - epidemiology Sepsis - microbiology Species Statistical analysis Transposons United Kingdom - epidemiology Virulence Virulence (Microbiology) Virulence - genetics Whole Genome Sequencing Whole genome sequencing, Klebsiella pneumoniae
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