SARS-CoV-2 PCR positivity rate and seroprevalence of related antibodies among a sample of patients in Cairo: Pre-wave 2 results of a screening program in a university hospital
Our study was carried out between May 5 and the end of October 2020. It included all patients requiring admission to Ain Shams University hospitals. An interview questionnaire was used to collect demographic and clinical data. Laboratory tests for all participants included RT-PCR and total antibody...
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| Veröffentlicht in: | PloS one 2021-07, Vol.16 (7), p.e0254581-e0254581 |
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| creator | Girgis, Samia A Hafez, Hala M Elarab, Hoda Ezz Sherif, Basma Sabry, Moshira H Afifi, Iman Hassan, Fatma Elzahraa Reda, Amira Elsayed, Shaimaa Mahmoud, Asmaa Habeb, Petra Habil, Ihab S Hussein, Rasha S Mossad, Isis M Mansour, Ossama Omar, Ashraf Saleh, Ayman M El-Meteini, Mahmoud |
| description | Our study was carried out between May 5 and the end of October 2020. It included all patients requiring admission to Ain Shams University hospitals. An interview questionnaire was used to collect demographic and clinical data. Laboratory tests for all participants included RT-PCR and total antibody assay for SARS-CoV-2. A total of 4,313 subjects were enrolled in our study, with females representing 56% of the sample. Adults and middle-aged individuals represented around 60% of the study sample. The positivity rate of SARS-CoV-2 PCR was 3.84% (95% CI 3.29-4.48), and the SARS-CoV-2 antibody seroprevalence was 29.82% (95% CI: 28.16-31.51). Males showed a higher risk for getting the COVID-19 infection, while middle-age group had significantly higher antibody seroprevalence rates. SARS-CoV-2 infection imposes a high burden on the community as detected by high seroprevalence rates. |
| doi_str_mv | 10.1371/journal.pone.0254581 |
| format | Article |
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It included all patients requiring admission to Ain Shams University hospitals. An interview questionnaire was used to collect demographic and clinical data. Laboratory tests for all participants included RT-PCR and total antibody assay for SARS-CoV-2. A total of 4,313 subjects were enrolled in our study, with females representing 56% of the sample. Adults and middle-aged individuals represented around 60% of the study sample. The positivity rate of SARS-CoV-2 PCR was 3.84% (95% CI 3.29-4.48), and the SARS-CoV-2 antibody seroprevalence was 29.82% (95% CI: 28.16-31.51). Males showed a higher risk for getting the COVID-19 infection, while middle-age group had significantly higher antibody seroprevalence rates. 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| issn | 1932-6203 1932-6203 |
| language | eng |
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| source | Public Library of Science (PLoS) Journals Open Access; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Antibodies Asymptomatic Biology and life sciences Coronaviruses COVID-19 Diabetes Disease control Disease transmission Epidemics Epidemiology Evaluation Health aspects Health surveillance Hospitals Infections Laboratory tests Medical laboratories Medical research Medical screening Medicine Medicine and health sciences Pathology Patients People and Places Polymerase chain reaction Questionnaires Serology Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Supervision Viral antibodies Viral diseases |
| title | SARS-CoV-2 PCR positivity rate and seroprevalence of related antibodies among a sample of patients in Cairo: Pre-wave 2 results of a screening program in a university hospital |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-18T09%3A44%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=SARS-CoV-2%20PCR%20positivity%20rate%20and%20seroprevalence%20of%20related%20antibodies%20among%20a%20sample%20of%20patients%20in%20Cairo:%20Pre-wave%202%20results%20of%20a%20screening%20program%20in%20a%20university%20hospital&rft.jtitle=PloS%20one&rft.au=Girgis,%20Samia%20A&rft.date=2021-07-15&rft.volume=16&rft.issue=7&rft.spage=e0254581&rft.epage=e0254581&rft.pages=e0254581-e0254581&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0254581&rft_dat=%3Cgale_plos_%3EA668604125%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2552047784&rft_id=info:pmid/34265021&rft_galeid=A668604125&rft_doaj_id=oai_doaj_org_article_0c2b9435a0c74056b87a98020b29afc4&rfr_iscdi=true |