Ultrafiltration Rate Effects Declines in Residual Kidney Function in Hemodialysis Patients

Background: High ultrafiltration rate (UFR) has been associated with increased mortality in hemodialysis (HD) patients. However, the impact of UFR on decline of residual kidney function (RKF) has not been elucidated among patients receiving conventional HD. Methods: We performed a retrospective coho...

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Veröffentlicht in:	American journal of nephrology 2019-12, Vol.50 (6), p.481-488
Hauptverfasser:	Lee, Yuji, Okuda, Yusuke, Sy, John, Kim, Sung Rok, Obi, Yoshitsugu, Kovesdy, Csaba P., Rhee, Connie M., Streja, Elani, Kalantar-Zadeh, Kamyar
Format:	Artikel
Sprache:	eng
Schlagworte:	Complications and side effects Hemodialysis Kidney function tests Patient outcomes Patient-Oriented, Translational Research: Research Article Statistics Ultrafiltration
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Zusammenfassung:	Background: High ultrafiltration rate (UFR) has been associated with increased mortality in hemodialysis (HD) patients. However, the impact of UFR on decline of residual kidney function (RKF) has not been elucidated among patients receiving conventional HD. Methods: We performed a retrospective cohort study of 7,753 patients who initiated conventional HD from 2007 to 2011 and survived the first year of dialysis with baseline UFR and renal urea clearance (KRU) data at baseline and 1 year (5th patient-quarter). The primary exposure was average UFR at the 1st patient-quarter from dialysis initiation (
ISSN:	0250-8095 1421-9670
DOI:	10.1159/000503918