Epidemiology of Preventable Drug-Related Problems
Aim: Drug-related problems (DRPs) "are the unwanted effects of drugs that potentially lead to a harmful outcome" thereby requiring considerable attention. Hospitalized pediatric patients, in particular, represent a population at risk of DRPs. The epidemiology of preventable DRPs among chil...
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| Veröffentlicht in: | Drug, healthcare and patient safety healthcare and patient safety, 2019-12, p.95 |
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| container_title | Drug, healthcare and patient safety |
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| creator | Alazmi, Aeshah Elzain, Rawan Mohammed Algarni, Hanan Al Shaikh, Adnan Al Thubaiti, Rihad S Aseeri, Mohammed Ahmed, Omaima Alhamdan, Hani |
| description | Aim: Drug-related problems (DRPs) "are the unwanted effects of drugs that potentially lead to a harmful outcome" thereby requiring considerable attention. Hospitalized pediatric patients, in particular, represent a population at risk of DRPs. The epidemiology of preventable DRPs among children in Saudi Arabia remains scarce, which thus poses distinct challenges to all healthcare professionals. We aim to characterize preventable DRPs among hospitalized children at KAMC-Jeddah. Methods: A prospective observational study of children ([less than or equal to]15 years) admitted to pediatric units (excluding cancer units) at KAMC-Jeddah over a 3-month period (May 29 to August 30, 2016) is carried out to determine the incidence of preventable DRPs and investigate the possible associated factors (gender, age, admission location, type of admission, and number of medications). Results: A total of 319 DRPs were identified among 235 patients, of which 280 DRPs (87.8%, 280/319) were deemed preventable. The majority of preventable DRPs were related to dose selection (78%, 219/280). None of the preventable DRPs were life threatening or fatal, and the majority were assessed as moderate in severity (94.3%, 264/280). There was no significant difference between DRP incidences with age mean 3.5 (P=0.389), gender mean (P=0.436), and weight mean 13.47 (P=0.323). Younger children (age [less than or equal to]2years) admitted to PICU were more likely to have DRP (OR 4.44, 95% CI, 1.87 to 10.52, P=0.00001). Scheduled admissions were 2.89 times more likely to be exposed to DRP compared to transferred admissions (OR 2.8, 95% CI, 1.83 to 4.70, P=0.005). Additionally, DRP incidences increased proportionally to the number of medications. Conclusion: Our data suggest that establishing appropriate prevention strategies towards improvement and safety in medicine use among this vulnerable patient population is a high priority. Keywords: children, risk factors, drug-related problems, hospitalized pediatric patients |
| format | Article |
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Hospitalized pediatric patients, in particular, represent a population at risk of DRPs. The epidemiology of preventable DRPs among children in Saudi Arabia remains scarce, which thus poses distinct challenges to all healthcare professionals. We aim to characterize preventable DRPs among hospitalized children at KAMC-Jeddah. Methods: A prospective observational study of children ([less than or equal to]15 years) admitted to pediatric units (excluding cancer units) at KAMC-Jeddah over a 3-month period (May 29 to August 30, 2016) is carried out to determine the incidence of preventable DRPs and investigate the possible associated factors (gender, age, admission location, type of admission, and number of medications). Results: A total of 319 DRPs were identified among 235 patients, of which 280 DRPs (87.8%, 280/319) were deemed preventable. The majority of preventable DRPs were related to dose selection (78%, 219/280). None of the preventable DRPs were life threatening or fatal, and the majority were assessed as moderate in severity (94.3%, 264/280). There was no significant difference between DRP incidences with age mean 3.5 (P=0.389), gender mean (P=0.436), and weight mean 13.47 (P=0.323). Younger children (age [less than or equal to]2years) admitted to PICU were more likely to have DRP (OR 4.44, 95% CI, 1.87 to 10.52, P=0.00001). Scheduled admissions were 2.89 times more likely to be exposed to DRP compared to transferred admissions (OR 2.8, 95% CI, 1.83 to 4.70, P=0.005). Additionally, DRP incidences increased proportionally to the number of medications. Conclusion: Our data suggest that establishing appropriate prevention strategies towards improvement and safety in medicine use among this vulnerable patient population is a high priority. Keywords: children, risk factors, drug-related problems, hospitalized pediatric patients</description><identifier>ISSN: 1179-1365</identifier><identifier>EISSN: 1179-1365</identifier><language>eng</language><publisher>Dove Medical Press Limited</publisher><subject>Child health ; Children ; Drugs ; Epidemiology ; Medical personnel ; Pediatrics</subject><ispartof>Drug, healthcare and patient safety, 2019-12, p.95</ispartof><rights>COPYRIGHT 2019 Dove Medical Press Limited</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Alazmi, Aeshah</creatorcontrib><creatorcontrib>Elzain, Rawan Mohammed</creatorcontrib><creatorcontrib>Algarni, Hanan</creatorcontrib><creatorcontrib>Al Shaikh, Adnan</creatorcontrib><creatorcontrib>Al Thubaiti, Rihad S</creatorcontrib><creatorcontrib>Aseeri, Mohammed</creatorcontrib><creatorcontrib>Ahmed, Omaima</creatorcontrib><creatorcontrib>Alhamdan, Hani</creatorcontrib><title>Epidemiology of Preventable Drug-Related Problems</title><title>Drug, healthcare and patient safety</title><description>Aim: Drug-related problems (DRPs) "are the unwanted effects of drugs that potentially lead to a harmful outcome" thereby requiring considerable attention. Hospitalized pediatric patients, in particular, represent a population at risk of DRPs. The epidemiology of preventable DRPs among children in Saudi Arabia remains scarce, which thus poses distinct challenges to all healthcare professionals. We aim to characterize preventable DRPs among hospitalized children at KAMC-Jeddah. Methods: A prospective observational study of children ([less than or equal to]15 years) admitted to pediatric units (excluding cancer units) at KAMC-Jeddah over a 3-month period (May 29 to August 30, 2016) is carried out to determine the incidence of preventable DRPs and investigate the possible associated factors (gender, age, admission location, type of admission, and number of medications). Results: A total of 319 DRPs were identified among 235 patients, of which 280 DRPs (87.8%, 280/319) were deemed preventable. The majority of preventable DRPs were related to dose selection (78%, 219/280). None of the preventable DRPs were life threatening or fatal, and the majority were assessed as moderate in severity (94.3%, 264/280). There was no significant difference between DRP incidences with age mean 3.5 (P=0.389), gender mean (P=0.436), and weight mean 13.47 (P=0.323). Younger children (age [less than or equal to]2years) admitted to PICU were more likely to have DRP (OR 4.44, 95% CI, 1.87 to 10.52, P=0.00001). Scheduled admissions were 2.89 times more likely to be exposed to DRP compared to transferred admissions (OR 2.8, 95% CI, 1.83 to 4.70, P=0.005). Additionally, DRP incidences increased proportionally to the number of medications. Conclusion: Our data suggest that establishing appropriate prevention strategies towards improvement and safety in medicine use among this vulnerable patient population is a high priority. Keywords: children, risk factors, drug-related problems, hospitalized pediatric patients</description><subject>Child health</subject><subject>Children</subject><subject>Drugs</subject><subject>Epidemiology</subject><subject>Medical personnel</subject><subject>Pediatrics</subject><issn>1179-1365</issn><issn>1179-1365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNpjYuA0NDS31DU0NjNlQWJzMPAWF2cZAIGxpZGJhREng6FrQWZKam5mfk5-eqVCfppCQFFqWWpeSWJSTqqCS1Fpum5Qak5iSWoKUCIfKJZbzMPAmpaYU5zKC6W5GdTcXEOcPXTTE3NS4zNSE3NKMorzc0pLMvPziuMdzQwNTYxNzYEE0QoBSHE3kw</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Alazmi, Aeshah</creator><creator>Elzain, Rawan Mohammed</creator><creator>Algarni, Hanan</creator><creator>Al Shaikh, Adnan</creator><creator>Al Thubaiti, Rihad S</creator><creator>Aseeri, Mohammed</creator><creator>Ahmed, Omaima</creator><creator>Alhamdan, Hani</creator><general>Dove Medical Press Limited</general><scope/></search><sort><creationdate>20191201</creationdate><title>Epidemiology of Preventable Drug-Related Problems</title><author>Alazmi, Aeshah ; Elzain, Rawan Mohammed ; Algarni, Hanan ; Al Shaikh, Adnan ; Al Thubaiti, Rihad S ; Aseeri, Mohammed ; Ahmed, Omaima ; Alhamdan, Hani</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-gale_healthsolutions_A6114357143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Child health</topic><topic>Children</topic><topic>Drugs</topic><topic>Epidemiology</topic><topic>Medical personnel</topic><topic>Pediatrics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alazmi, Aeshah</creatorcontrib><creatorcontrib>Elzain, Rawan Mohammed</creatorcontrib><creatorcontrib>Algarni, Hanan</creatorcontrib><creatorcontrib>Al Shaikh, Adnan</creatorcontrib><creatorcontrib>Al Thubaiti, Rihad S</creatorcontrib><creatorcontrib>Aseeri, Mohammed</creatorcontrib><creatorcontrib>Ahmed, Omaima</creatorcontrib><creatorcontrib>Alhamdan, Hani</creatorcontrib><jtitle>Drug, healthcare and patient safety</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alazmi, Aeshah</au><au>Elzain, Rawan Mohammed</au><au>Algarni, Hanan</au><au>Al Shaikh, Adnan</au><au>Al Thubaiti, Rihad S</au><au>Aseeri, Mohammed</au><au>Ahmed, Omaima</au><au>Alhamdan, Hani</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiology of Preventable Drug-Related Problems</atitle><jtitle>Drug, healthcare and patient safety</jtitle><date>2019-12-01</date><risdate>2019</risdate><spage>95</spage><pages>95-</pages><issn>1179-1365</issn><eissn>1179-1365</eissn><abstract>Aim: Drug-related problems (DRPs) "are the unwanted effects of drugs that potentially lead to a harmful outcome" thereby requiring considerable attention. Hospitalized pediatric patients, in particular, represent a population at risk of DRPs. The epidemiology of preventable DRPs among children in Saudi Arabia remains scarce, which thus poses distinct challenges to all healthcare professionals. We aim to characterize preventable DRPs among hospitalized children at KAMC-Jeddah. Methods: A prospective observational study of children ([less than or equal to]15 years) admitted to pediatric units (excluding cancer units) at KAMC-Jeddah over a 3-month period (May 29 to August 30, 2016) is carried out to determine the incidence of preventable DRPs and investigate the possible associated factors (gender, age, admission location, type of admission, and number of medications). Results: A total of 319 DRPs were identified among 235 patients, of which 280 DRPs (87.8%, 280/319) were deemed preventable. The majority of preventable DRPs were related to dose selection (78%, 219/280). None of the preventable DRPs were life threatening or fatal, and the majority were assessed as moderate in severity (94.3%, 264/280). There was no significant difference between DRP incidences with age mean 3.5 (P=0.389), gender mean (P=0.436), and weight mean 13.47 (P=0.323). Younger children (age [less than or equal to]2years) admitted to PICU were more likely to have DRP (OR 4.44, 95% CI, 1.87 to 10.52, P=0.00001). Scheduled admissions were 2.89 times more likely to be exposed to DRP compared to transferred admissions (OR 2.8, 95% CI, 1.83 to 4.70, P=0.005). Additionally, DRP incidences increased proportionally to the number of medications. Conclusion: Our data suggest that establishing appropriate prevention strategies towards improvement and safety in medicine use among this vulnerable patient population is a high priority. Keywords: children, risk factors, drug-related problems, hospitalized pediatric patients</abstract><pub>Dove Medical Press Limited</pub></addata></record> |
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| source | Taylor & Francis Open Access; DOVE Medical Press Journals; DOAJ Directory of Open Access Journals; PubMed Central Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Child health Children Drugs Epidemiology Medical personnel Pediatrics |
| title | Epidemiology of Preventable Drug-Related Problems |
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