The phosphoinositide-3-kinase

The functional relevance of the B-cell receptor (BCR) and the evolution of protein kinases as therapeutic targets have recently shifted the paradigm for treatment of B-cell malignancies. Inhibition of p110[delta] with idelalisib has shown clinical activity in chronic lymphocytic leukemia (CLL). The...

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Veröffentlicht in:	Leukemia 2015-09, Vol.29 (9), p.1811
Hauptverfasser:	Peluso, M, Wierda, W G, Balakrishnan, K, Burger, J A, Fu, M, Rosin, N Y, Keating, M J
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Cell receptors Chronic lymphocytic leukemia Development and progression Genetic aspects Health aspects Phosphotransferases
Online-Zugang:	Volltext
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