Association between glycated hemoglobin
Background: To investigate the association between glycated hemoglobin (HbAlc) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA). Methods: The present retrospective cross-sectional study was accomplished at the Faculty of...
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| Veröffentlicht in: | Diabetes, metabolic syndrome and obesity metabolic syndrome and obesity, 2019-09, p.1639 |
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| creator | Alzahrani, Sami Hamdan Baig, Mukhtiar Alqarni, Dalya Abdulrahman Bakhamees, Wael Hassan Aashi, Mooataz Mohammed Al-Shaibi, Faisal Khaled |
| description | Background: To investigate the association between glycated hemoglobin (HbAlc) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA). Methods: The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date. Results: The participants' data were analyzed gender-wise. The females had significantly higher values for BMI (p=0.002), HbA1c (p=0.009), triglycerides (TGs) (p |
| format | Article |
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Methods: The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date. Results: The participants' data were analyzed gender-wise. The females had significantly higher values for BMI (p=0.002), HbA1c (p=0.009), triglycerides (TGs) (p<0.001), high-density lipoprotein cholesterol (HDL-C) (p=0.002) and low-density lipoprotein cholesterol (LDL-C) (p<0.001) compared to the males. The study subjects were grouped according to their level of HbA1c (good glycemic index <7%, and poor glycemic index >7%). In both groups, no significant differences were found in any of the parameters other than TGs (p=0.020) and HbA1c (p<0.001). An analysis of the correlation between HbA1c and other parameters exhibited a significant correlation with TG (r=0.16, p=0.020), while no significant relationship was observed with the other variables. The linear regression results indicated that HbA1c values were associated with TGs (p=0.020) and were independent of age, BMI, TC, LDL-C, HDL-C and FPG levels. Conclusion: The glycated Hb was associated with TGs, and no significant association was found with age, BMI, TC, LDL-C, HDL-C and FPG levels. Keywords: glycated hemoglobin, DMT2, glycemic control, dyslipidemia, lipid profile</description><identifier>ISSN: 1178-7007</identifier><identifier>EISSN: 1178-7007</identifier><language>eng</language><publisher>Dove Medical Press Limited</publisher><subject>Analysis ; Biochemistry ; Care and treatment ; Diabetes mellitus ; Diabetes therapy ; Fasting ; Glucose ; Glycemic index ; Glycosylated hemoglobin ; Hemoglobins ; Low density lipoproteins ; Medical research ; Physicians ; Regression analysis ; Triglycerides ; Type 2 diabetes</subject><ispartof>Diabetes, metabolic syndrome and obesity, 2019-09, p.1639</ispartof><rights>COPYRIGHT 2019 Dove Medical Press Limited</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Alzahrani, Sami Hamdan</creatorcontrib><creatorcontrib>Baig, Mukhtiar</creatorcontrib><creatorcontrib>Alqarni, Dalya Abdulrahman</creatorcontrib><creatorcontrib>Bakhamees, Wael Hassan</creatorcontrib><creatorcontrib>Aashi, Mooataz Mohammed</creatorcontrib><creatorcontrib>Al-Shaibi, Faisal Khaled</creatorcontrib><title>Association between glycated hemoglobin</title><title>Diabetes, metabolic syndrome and obesity</title><description>Background: To investigate the association between glycated hemoglobin (HbAlc) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA). Methods: The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date. Results: The participants' data were analyzed gender-wise. The females had significantly higher values for BMI (p=0.002), HbA1c (p=0.009), triglycerides (TGs) (p<0.001), high-density lipoprotein cholesterol (HDL-C) (p=0.002) and low-density lipoprotein cholesterol (LDL-C) (p<0.001) compared to the males. The study subjects were grouped according to their level of HbA1c (good glycemic index <7%, and poor glycemic index >7%). In both groups, no significant differences were found in any of the parameters other than TGs (p=0.020) and HbA1c (p<0.001). An analysis of the correlation between HbA1c and other parameters exhibited a significant correlation with TG (r=0.16, p=0.020), while no significant relationship was observed with the other variables. The linear regression results indicated that HbA1c values were associated with TGs (p=0.020) and were independent of age, BMI, TC, LDL-C, HDL-C and FPG levels. Conclusion: The glycated Hb was associated with TGs, and no significant association was found with age, BMI, TC, LDL-C, HDL-C and FPG levels. Keywords: glycated hemoglobin, DMT2, glycemic control, dyslipidemia, lipid profile</description><subject>Analysis</subject><subject>Biochemistry</subject><subject>Care and treatment</subject><subject>Diabetes mellitus</subject><subject>Diabetes therapy</subject><subject>Fasting</subject><subject>Glucose</subject><subject>Glycemic index</subject><subject>Glycosylated hemoglobin</subject><subject>Hemoglobins</subject><subject>Low density lipoproteins</subject><subject>Medical research</subject><subject>Physicians</subject><subject>Regression analysis</subject><subject>Triglycerides</subject><subject>Type 2 diabetes</subject><issn>1178-7007</issn><issn>1178-7007</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNpjYuA0NDS30DU3MDBnQWJzMPAWF2cZgIC5gYmRESeDumNxcX5yZmJJZn6eQlJqSXlqap5Cek5lcmJJaopCRmpufnpOflJmHg8Da1piTnEqL5TmZlBzcw1x9tBNT8xJjc9ITcwpySjOzykFmVMc72hmYGJobgi0xZhohQAQ0jQs</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Alzahrani, Sami Hamdan</creator><creator>Baig, Mukhtiar</creator><creator>Alqarni, Dalya Abdulrahman</creator><creator>Bakhamees, Wael Hassan</creator><creator>Aashi, Mooataz Mohammed</creator><creator>Al-Shaibi, Faisal Khaled</creator><general>Dove Medical Press Limited</general><scope/></search><sort><creationdate>20190901</creationdate><title>Association between glycated hemoglobin</title><author>Alzahrani, Sami Hamdan ; Baig, Mukhtiar ; Alqarni, Dalya Abdulrahman ; Bakhamees, Wael Hassan ; Aashi, Mooataz Mohammed ; Al-Shaibi, Faisal Khaled</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-gale_healthsolutions_A6041710073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Analysis</topic><topic>Biochemistry</topic><topic>Care and treatment</topic><topic>Diabetes mellitus</topic><topic>Diabetes therapy</topic><topic>Fasting</topic><topic>Glucose</topic><topic>Glycemic index</topic><topic>Glycosylated hemoglobin</topic><topic>Hemoglobins</topic><topic>Low density lipoproteins</topic><topic>Medical research</topic><topic>Physicians</topic><topic>Regression analysis</topic><topic>Triglycerides</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alzahrani, Sami Hamdan</creatorcontrib><creatorcontrib>Baig, Mukhtiar</creatorcontrib><creatorcontrib>Alqarni, Dalya Abdulrahman</creatorcontrib><creatorcontrib>Bakhamees, Wael Hassan</creatorcontrib><creatorcontrib>Aashi, Mooataz Mohammed</creatorcontrib><creatorcontrib>Al-Shaibi, Faisal Khaled</creatorcontrib><jtitle>Diabetes, metabolic syndrome and obesity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alzahrani, Sami Hamdan</au><au>Baig, Mukhtiar</au><au>Alqarni, Dalya Abdulrahman</au><au>Bakhamees, Wael Hassan</au><au>Aashi, Mooataz Mohammed</au><au>Al-Shaibi, Faisal Khaled</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between glycated hemoglobin</atitle><jtitle>Diabetes, metabolic syndrome and obesity</jtitle><date>2019-09-01</date><risdate>2019</risdate><spage>1639</spage><pages>1639-</pages><issn>1178-7007</issn><eissn>1178-7007</eissn><abstract>Background: To investigate the association between glycated hemoglobin (HbAlc) and the lipid profile in patients with type 2 diabetes mellitus (T2DM) at a tertiary care hospital in Jeddah, Saudi Arabia (SA). Methods: The present retrospective cross-sectional study was accomplished at the Faculty of Medicine, King Abdulaziz University (KAU), Jeddah, SA, between April and July 2018. There were 206 T2DM patients selected for the study (141 females and 65 males), and the data were collected through a review of the electronic profiles of patients by using the medical electronic file system used at the KAU Hospital. Biochemical data such as fasting plasma glucose (FPG), HbA1c and lipid profile, along with the patient's age, BMI and gender, were also taken from the electronic file system. The inclusion criteria allowed for only patients who were regularly seeing their physician and whose electronic file was up to date. Results: The participants' data were analyzed gender-wise. The females had significantly higher values for BMI (p=0.002), HbA1c (p=0.009), triglycerides (TGs) (p<0.001), high-density lipoprotein cholesterol (HDL-C) (p=0.002) and low-density lipoprotein cholesterol (LDL-C) (p<0.001) compared to the males. The study subjects were grouped according to their level of HbA1c (good glycemic index <7%, and poor glycemic index >7%). In both groups, no significant differences were found in any of the parameters other than TGs (p=0.020) and HbA1c (p<0.001). An analysis of the correlation between HbA1c and other parameters exhibited a significant correlation with TG (r=0.16, p=0.020), while no significant relationship was observed with the other variables. The linear regression results indicated that HbA1c values were associated with TGs (p=0.020) and were independent of age, BMI, TC, LDL-C, HDL-C and FPG levels. Conclusion: The glycated Hb was associated with TGs, and no significant association was found with age, BMI, TC, LDL-C, HDL-C and FPG levels. Keywords: glycated hemoglobin, DMT2, glycemic control, dyslipidemia, lipid profile</abstract><pub>Dove Medical Press Limited</pub></addata></record> |
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| source | DOAJ Directory of Open Access Journals; Dove Press Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Access via Taylor & Francis (Open Access Collection); PubMed Central |
| subjects | Analysis Biochemistry Care and treatment Diabetes mellitus Diabetes therapy Fasting Glucose Glycemic index Glycosylated hemoglobin Hemoglobins Low density lipoproteins Medical research Physicians Regression analysis Triglycerides Type 2 diabetes |
| title | Association between glycated hemoglobin |
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