Associations of Pulse and Blood Pressure with Hippocampal Volume by APOE and Cognitive Phenotype: The Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Background: It is increasingly evident that high blood pressure can promote reduction in global and regional brain volumes. While these effects may preferentially affect the hippocampus, reports are inconsistent. Methods: Using data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI), we exa...

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Veröffentlicht in:	Dementia and geriatric cognitive disorders 2018-01, Vol.45 (1-2), p.66-78
Hauptverfasser:	Ngwa, Julius S., Fungwe, Thomas V., Ntekim, Oyonumo, Allard, Joanne S., Johnson, Sheree M., Castor, Chimene, Graham, Lennox, Nadarajah, Sheeba, Gillum, Richard F., Obisesan, Thomas O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Aged Aged, 80 and over Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer Disease - psychology Alzheimer's disease Apolipoproteins Apolipoproteins E - genetics Associations Blood Pressure Brain Brain research Cognition Cognitive Dysfunction - genetics Cognitive Dysfunction - pathology Cognitive Dysfunction - psychology Diagnostic imaging Female Genetic aspects Genotype Heart Rate Hippocampus - pathology Humans Hypertension Magnetic Resonance Imaging Male Neuroimaging Neuropsychological Tests Original Research Article Prodromal Symptoms
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