Late stent thrombosis in a patient with

Late stent thrombosis in a patient with

Recurrent thrombotic events still occur despite dual antiplatelet therapy in patient's post percutaneous coronary intervention (PCI) could be attributed to high on-treatment platelet reactivity. A 44-year-old male, who had staged PCI to left anterior descending (LAD) 2 weeks after an anterior M...

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Veröffentlicht in:Pharmacogenomics 2018-10, Vol.19 (15), p.1151-1157
Hauptverfasser: Tan, Shirley Siang Ning, Koh, Keng Tat, Tiong, Lee Len, Ong, Tiong Kiam, Fong, Alan Yean Yip
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late stent thrombosis
point-of-care genotyping
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container_end_page 1157
container_issue 15
container_start_page 1151
container_title Pharmacogenomics
container_volume 19
creator Tan, Shirley Siang Ning
Koh, Keng Tat
Tiong, Lee Len
Ong, Tiong Kiam
Fong, Alan Yean Yip
description Recurrent thrombotic events still occur despite dual antiplatelet therapy in patient's post percutaneous coronary intervention (PCI) could be attributed to high on-treatment platelet reactivity. A 44-year-old male, who had staged PCI to left anterior descending (LAD) 2 weeks after an anterior MI, with a drug-coated stent was readmitted with new anterior STEMI 35 days later. Coronary angiogram revealed mid-stent thrombus . He had further uncomplicated PCI. Platelet function testing and genotyping showed clopidogrel high on-treatment platelet reactivity and genotype. Ticagrelor was commenced. This case study is the first reported in Malaysia to document a patient with a genotype presenting with a stent thrombosis after an uncomplicated index PCI procedure.
doi_str_mv 10.2217/pgs-2018-0082
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subjects late stent thrombosis
point-of-care genotyping
title Late stent thrombosis in a patient with
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