Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo

At the site of injury activated platelets release various mediators, one of which is sphingosine 1-phosphate (S1P). It was the aim of this study to explore whether activated human platelets had a pronociceptive effect in an in vivo mouse model and whether this effect was based on the release of S1P...

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Hauptverfasser: Weth, D, Benetti, C, Rauch, C, Gstraunthaler, G, Schmidt, H, Geisslinger, G, Sabbadini, R, Proia, R.L, Kress, M
Format: Artikel
Sprache:eng
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