Genetic requirements for the single-strand annealing pathways of double-strand break repair in Saccharomyces cerevisiae

HO endonuclease-induced double-strand breaks (DSBs) within a direct duplication of Escherichia coli lacZ genes are repaired either by gene conversion or by single-strand annealing (SSA), with 80% being SSA. Previously it was demonstrated that the RAD52 gene is required for DSB-induced SSA. In the pr...

Ausführliche Beschreibung