RAD3 protein of Saccharomyces cerevisiae is a DNA helicase

The Saccharomyces cerevisiae RAD3 gene, which is required for cell viability and excision repair of damaged DNA, encodes an 89-kDa protein that has a single-stranded DNA-dependent ATPase activity. We now show that the RAD3 protein also possesses a helicase activity that unwinds duplex regions in DNA...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1987-12, Vol.84 (24), p.8951-8955
Hauptverfasser:	Sung, P, Prakash, L, Matson, S.W, Prakash, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatases ADN Antigen-Antibody Reactions ATPASE Biological and medical sciences DNA DNA damage DNA Helicases - isolation & purification DNA Helicases - physiology DNA Repair DNA Replication Enzymes Fundamental and applied biological sciences. Psychology Fungal Proteins - isolation & purification Fungal Proteins - physiology Gels GENE GENES Growth, nutrition, metabolism, transports, enzymes. Molecular biology HIDROLASAS HYDROLASE HYDROLASES Microbiology Mycology Nucleotides PROTEINAS PROTEINE PROTEINS SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - physiology Single stranded DNA Yeasts
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