Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

Biomaterials that mimic aspects of the extracellular matrix by presenting a 3D microenvironment that cells can locally degrade and remodel are finding increased applications as wound-healing matrices, tissue engineering scaffolds, and even substrates for stem cell expansion. In vivo, cells do not si...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2015, Vol.112 (29), p.E3757-E3764
Hauptverfasser: Schultz, Kelly M, Kyle A. Kyburz, Kristi S. Anseth
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Sprache:eng
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