Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the α4 integrin

Dynamic signals linking the actin cytoskeleton and cell adhesion receptors are essential for morphogenesis during development and normal tissue homeostasis. Abi1 is a central regulator of actin polymerization through interactions with multiple protein complexes. However, the in vivo role of Abi1 rem...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2011, Vol.108 (1), p.149-154
Hauptverfasser:	Ring, Colleen, Ginsberg, Mark H, Haling, Jacob, Pendergast, Ann Marie
Format:	Artikel
Sprache:	eng
Schlagworte:	actin adhesion cell adhesion cell movement homeostasis integrins mice microfilaments morphogenesis mutants polymerization receptors
Online-Zugang:	Volltext
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