MerR-Like Regulator BrlR Impairs Pseudomonas aeruginosa Biofilm Tolerance to Colistin by Repressing PhoPQ

While the MerR-like transcriptional regulator BrlR has been demonstrated to contribute to Pseudomonas aeruginosa biofilm tolerance to antimicrobial agents known as multidrug efflux pump substrates, the role of BrlR in resistance to cationic antimicrobial peptides (CAP), which is based on reduced out...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Bacteriology 2013-10, Vol.195 (20), p.4678-4688
Hauptverfasser:	Chambers, Jacob R, Sauer, Karin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Antibiotics Antimicrobial agents antimicrobial cationic peptides Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology biofilm Biofilms Biofilms - drug effects colistin Colistin - metabolism Colistin - pharmacology Correlation analysis DNA Down-Regulation Drug resistance Drug Resistance, Bacterial - genetics Gene Expression Regulation, Bacterial - drug effects gene overexpression Genotype & phenotype Inactivation Microbial Sensitivity Tests Multigene Family operon Peptides phenotype Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - metabolism tobramycin Tobramycin - pharmacology transcription factors transporters
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!