Pharmacokinetics of Cefovecin in Cynomolgus Macaques (Macaca fascicularis), Olive Baboons (Papio anubis), and Rhesus Macaques (Macaca mulatta)

Cefovecin sodium is a long-acting, third-generation, cephalosporin antibiotic approved for the treatment of skin infections in dogs and cats. The pharmacokinetic properties of cefovecin were evaluated in cynomolgus macaques (Macaca fascicularis), olive baboons (Papio anubis), and rhesus macaques (Ma...

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Veröffentlicht in:	Journal of the American Association for Laboratory Animal Science 2011-05, Vol.50 (3), p.389-395
Hauptverfasser:	Raabe, Brigitte M, Lovaglio, Jamie, Grover, G. Scott, Brown, Scott A, Boucher, Joseph F, Yuan, Yang, Civil, Jacqueline R, Gillhouse, Kimberly A, Stubbs, Makeida N, Hoggatt, Amber F, Halliday, Lisa C, Fortman, Jeffrey D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Laboratory - metabolism Anti-Infective Agents - blood Anti-Infective Agents - pharmacokinetics cats cefovecin Cephalosporins - blood Cephalosporins - pharmacokinetics dogs Experimental Use Female Glomerular Filtration Rate Half-Life Macaca fascicularis Macaca fascicularis - metabolism Macaca mulatta Macaca mulatta - metabolism Male mass spectrometry Monkey Diseases - drug therapy Monkey Diseases - prevention & control Papio anubis Papio anubis - metabolism pharmacokinetics renal clearance renal tubules Skin Diseases - drug therapy Skin Diseases - prevention & control Skin Diseases - veterinary sodium Species Specificity ultra-performance liquid chromatography
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