Phagocytic and oxidative burst activity of chicken thrombocytes to Salmonella, Escherichia coli and other bacteria

The potential role of chicken thrombocytes in immune responses to Salmonella, Escherichia coli and other bacteria was investigated by in vitro assays of phagocytosis and respiratory burst activity. Thrombocytes were found to phagocytose bacteria, but were found to be less phagocytic than heterophils...

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Veröffentlicht in:Avian pathology 1999-12, Vol.28 (6), p.567-572
Hauptverfasser: Wigley, P, Hulme, S.D, Barrow, P.A
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creator Wigley, P
Hulme, S.D
Barrow, P.A
description The potential role of chicken thrombocytes in immune responses to Salmonella, Escherichia coli and other bacteria was investigated by in vitro assays of phagocytosis and respiratory burst activity. Thrombocytes were found to phagocytose bacteria, but were found to be less phagocytic than heterophils. Oxidative burst activity was generated upon challenge of thrombocytes with various Salmonella strains, E. coli, three other bacterial species, and zymosan A. These findings indicate that thrombocytes may play a role in innate immunity to bacteria in the chicken.
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source IngentaConnect Free/Open Access Journals; EZB-FREE-00999 freely available EZB journals
subjects Bacteria
Birds
blood platelets
Burkholderia cepacia
chickens
Escherichia coli
immune response
Immune system
in vitro
Pathology
phagocytosis
Pseudomonas aeruginosa
Salmonella
Staphylococcus aureus
title Phagocytic and oxidative burst activity of chicken thrombocytes to Salmonella, Escherichia coli and other bacteria
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