Role of surface modulating assemblies in growth control of normal and transformed fibroblasts

Cellular microtubules, microfilaments, and surface receptors have been postulated to form a surface modulating assembly that regulates surface receptor mobility and cell growth. To test this hypothesis, we examined three agents known to affect cell growth [colchicine, concanavalin A (Con A), and the...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1977-02, Vol.74 (2), p.666-670
Hauptverfasser:	McClain, D.A, D'Eustachio, P, Edelman, G.M
Format:	Artikel
Sprache:	eng
Schlagworte:	animal science Animals Avian Sarcoma Viruses Cell cycle Cell Division Cell growth Cell Membrane - drug effects Cell Membrane - physiology Cell Transformation, Neoplastic - drug effects Cells, Cultured Chick Embryo Colchicine - pharmacology Concanavalin A DNA Replication - drug effects Fibroblasts Fibroblasts - physiology Interphase Kidney cells livestock Lymphocytes Protein synthesis Receptors src genes Time Factors Viruses zoology
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