Biochemical properties of encapsulated high-density 3-D HepG2 aggregates formed in an ultrasound trap for application in hepatotoxicity studies

This paper describes the alginate encapsulation of preformed high-density 3-D HepG2 cell aggregates that guarantees good maintenance of liver-specific biomarker expression. The process involves forming a high-density (≥7 × 10⁴ cells/aggregate) discoid 3-D cell aggregate in an ultrasound trap, which...

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Veröffentlicht in:Cell biology and toxicology 2010-04, Vol.26 (2), p.127-141
1. Verfasser: Bazou, Despina
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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