Identification of HCV protease inhibitor resistance mutations by selection pressure-based method

A major challenge to successful antiviral therapy is the emergence of drug-resistant viruses. Recent studies have developed several automated analyses of HIV sequence polymorphism based on calculations of selection pressure (Ka/Ks) to predict drug resistance mutations. Similar resistance analysis pr...

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Veröffentlicht in:	Nucleic acids research 2009, Vol.37 (10), p.1-7
Hauptverfasser:	Qiu, Ping, Sanfiorenzo, Vincent, Curry, Stephanie, Guo, Zhuyan, Liu, Shaotang, Skelton, Angela, Xia, Ellen, Cullen, Constance, Ralston, Robert, Greene, Jonathan, Tong, Xiao
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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