Effect of cholesterol on the structure of a phospholipid bilayer

Cholesterol plays an important role in regulating the properties of phospholipid membranes. To obtain a detailed understanding of the lipid-cholesterol interactions, we have developed a mesoscopic water-lipid-cholesterol model. In this model, we take into account the hydrophobic-hydrophilic interact...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-03, Vol.106 (10), p.3654-3658
Hauptverfasser:	de Meyer, Frédérick, Smit, Berend
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Cholesterol Cholesterol - chemistry Cholesterols Condensation Dimyristoylphosphatidylcholine - chemistry Experimental data Experiments Gels Lipid Bilayers - chemistry Lipids Membranes Models, Biological Molecular interactions Molecules P branes Phase diagrams Phospholipids Phospholipids - chemistry Physical Sciences
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