Comparative analysis of the sialic acid binding activity and the tropism for the respiratory epithelium of four different strains of avian infectious bronchitis virus

Avian infectious bronchitis virus (IBV) is a major pathogen in commercial poultry flocks. We recently demonstrated that sialic acid serves as a receptor determinant for IBV on the tracheal epithelium. Here we compared the IBV strains Beaudette, 4/91, Italy02, and QX for their sialic acid-binding pro...

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Veröffentlicht in:	Avian pathology 2009-02, Vol.38 (1), p.41-45
Hauptverfasser:	Abd El Rahman, S, El-Kenawy, A.A, Neumann, U, Herrler, G, Winter, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Avian flu Avian infectious bronchitis virus binding capacity cell culture Cells Chick Embryo chickens Comparative analysis epithelial cells epithelium goblet cells in vitro studies infectious bronchitis Infectious bronchitis virus Infectious bronchitis virus - classification Infectious bronchitis virus - physiology kidney cells Kidneys N-Acetylneuraminic Acid - metabolism Ornithology pathogenesis pathogenicity pathotypes Poultry receptors Respiratory Mucosa - cytology Respiratory Mucosa - virology sialic acids strain differences strains tissue tropism trachea (vertebrates) Trachea - cytology Tropism - physiology
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