Taxanes exported from Taxus X media Hicksii cuttings into liquid medium over time
Cuttings from Taxus X media Hicksii were maintained in Gamborg's B5 liquid culture medium, where 10-deacetyl baccatin III, baccatin III, 10-deacetyl taxol, cephalomannine, 7-epi-10-deacetyl taxol and taxol accumulated in the incubation medium over time. Greater amounts of each taxane were recov...
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| Veröffentlicht in: | Phytochemistry (Oxford) 1996, Vol.43 (1), p.95-98 |
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| container_title | Phytochemistry (Oxford) |
| container_volume | 43 |
| creator | Hoffman, A.M Voelker, C.C.J Franzen, A.T Shiotani, K.S Sandhu, J.S |
| description | Cuttings from Taxus X media Hicksii were maintained in Gamborg's B5 liquid culture medium, where 10-deacetyl baccatin III, baccatin III, 10-deacetyl taxol, cephalomannine, 7-epi-10-deacetyl taxol and taxol accumulated in the incubation medium over time. Greater amounts of each taxane were recovered from plant material as compared with liquid medium. Medium was removed and replaced weekly, biweekly or triweekly for up to nine weeks. The sum of all taxol recovered from the liquid that had been harvested from a yew cutting and extracted from the medium weekly over eight weeks was approximately equal to the amount of taxol which would be recovered from the fresh plant cutting, and the cutting still contained taxol. This suggests that in vitro cultures of yew cuttings may be a re-usable source of taxol and related taxanes. |
| doi_str_mv | 10.1016/0031-9422(96)00183-5 |
| format | Article |
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Greater amounts of each taxane were recovered from plant material as compared with liquid medium. Medium was removed and replaced weekly, biweekly or triweekly for up to nine weeks. The sum of all taxol recovered from the liquid that had been harvested from a yew cutting and extracted from the medium weekly over eight weeks was approximately equal to the amount of taxol which would be recovered from the fresh plant cutting, and the cutting still contained taxol. 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Greater amounts of each taxane were recovered from plant material as compared with liquid medium. Medium was removed and replaced weekly, biweekly or triweekly for up to nine weeks. The sum of all taxol recovered from the liquid that had been harvested from a yew cutting and extracted from the medium weekly over eight weeks was approximately equal to the amount of taxol which would be recovered from the fresh plant cutting, and the cutting still contained taxol. 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Greater amounts of each taxane were recovered from plant material as compared with liquid medium. Medium was removed and replaced weekly, biweekly or triweekly for up to nine weeks. The sum of all taxol recovered from the liquid that had been harvested from a yew cutting and extracted from the medium weekly over eight weeks was approximately equal to the amount of taxol which would be recovered from the fresh plant cutting, and the cutting still contained taxol. This suggests that in vitro cultures of yew cuttings may be a re-usable source of taxol and related taxanes.</abstract><doi>10.1016/0031-9422(96)00183-5</doi><tpages>4</tpages></addata></record> |
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| ispartof | Phytochemistry (Oxford), 1996, Vol.43 (1), p.95-98 |
| issn | 0031-9422 1873-3700 |
| language | eng |
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| source | ScienceDirect Journals (5 years ago - present) |
| subjects | chemical composition chemical constituents of plants culture filtrates derivatives diterpenoids in vitro culture isolation liquids paclitaxel plant cuttings quantitative analysis Taxus media |
| title | Taxanes exported from Taxus X media Hicksii cuttings into liquid medium over time |
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