Metabolism of 2,3,5,6-tetrachloronitrobenzene (tecnazene) in rat

1. The metabolic fate of [U-14C]-2,3,5,6-tetrachloronitrobenzene (tecnazene) has been determined in the male and female rat following a single dose of 1 mg/kg and in surgically prepared, bile-duct-cannulated rats following a single oral dose of 135 mg/kg. 2. Radioactivity in the female rat was excre...

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Veröffentlicht in:	Xenobiotica 1996, Vol.26 (1), p.65-77
Hauptverfasser:	Lappin, G.J, Pritchard, D, Moore, R.B, Laird, W.J.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals biochemical pathways Biological and medical sciences Biotransformation Chromatography, High Pressure Liquid excretion feces Feces - chemistry Female Fungicides, Industrial - pharmacokinetics Gas Chromatography-Mass Spectrometry Male Mass Spectrometry Medical sciences metabolism metabolites Nitrobenzenes - pharmacokinetics Pesticides, fertilizers and other agrochemicals toxicology pharmacokinetics Rats Rats, Wistar tecnazene Tissue Distribution Toxicology urine
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