FOXO1 Represses Peroxisome Proliferator-activated Receptor-γ1 and -γ2 Gene Promoters in Primary Adipocytes: A NOVEL PARADIGM TO INCREASE INSULIN SENSITIVITY
FOXO1 and peroxisome proliferator-activated receptor-γ (PPARγ) are crucial transcription factors that regulate glucose metabolism and insulin responsiveness in insulin target tissues. We have shown that, in primary rat adipocytes, both factors regulate transcription of the insulin-responsive GLUT4 g...
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Veröffentlicht in: | The Journal of biological chemistry 2006-07, Vol.281 (29), p.19881-19891 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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