FOXO1 Represses Peroxisome Proliferator-activated Receptor-γ1 and -γ2 Gene Promoters in Primary Adipocytes: A NOVEL PARADIGM TO INCREASE INSULIN SENSITIVITY

FOXO1 and peroxisome proliferator-activated receptor-γ (PPARγ) are crucial transcription factors that regulate glucose metabolism and insulin responsiveness in insulin target tissues. We have shown that, in primary rat adipocytes, both factors regulate transcription of the insulin-responsive GLUT4 g...

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Veröffentlicht in:The Journal of biological chemistry 2006-07, Vol.281 (29), p.19881-19891
Hauptverfasser: Armoni, Michal, Harel, Chava, Karni, Shiri, Chen, Hui, Bar-Yoseph, Fabiana, Ver, Marel R, Quon, Michael J, Karnieli, Eddy
Format: Artikel
Sprache:eng
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