Development and Optimization of High-Throughput Methods To Measure Plasmodium falciparum-Specific Growth Inhibitory Antibodies

Antibodies that inhibit replication of Plasmodium falciparum in erythrocytes are thought to be important both in acquired immunity to malaria and as mediators of immunity generated by candidate blood-stage vaccines. However, several constraints have limited the study of these functional antibodies i...

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Veröffentlicht in:	Journal of Clinical Microbiology 2006-05, Vol.44 (5), p.1665-1673
Hauptverfasser:	Persson, Kristina E.M, Lee, Chee T, Marsh, Kevin, Beeson, James G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - analysis Antibodies, Protozoan - blood Biological and medical sciences Erythrocytes - parasitology Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Infectious diseases Malaria Vaccines - immunology Malaria, Falciparum - immunology Malaria, Falciparum - parasitology Medical sciences Microbiology Parasitemia - immunology Parasitemia - parasitology Parasitology Plasmodium falciparum Plasmodium falciparum - growth & development Plasmodium falciparum - immunology Sensitivity and Specificity
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