Lamina-associated polypeptide 2[alpha] regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway

Lamina-associated polypeptide (LAP) 2[alpha] is a nonmembrane-bound LAP2 isoform that forms complexes with nucleoplasmic A-type lamins. In this study, we show that the overexpression of LAP2[alpha] in fibroblasts reduced proliferation and delayed entry into the cell cycle from a G0 arrest. In contra...

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Veröffentlicht in:	The Journal of cell biology 2006, Vol.173 (1), p.83-93
Hauptverfasser:	Dorner, Daniela, Vlcek, Sylvia, Foeger, Nicole, Gajewski, Andreas, Makolm, Christian, Gotzmann, Josef, Hutchison, Christopher J, Foisner, Roland
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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