alpha(2)-Heremans-Schmid Glycoprotein/ Fetuin-A Is Associated With Insulin Resistance and Fat Accumulation in the Liver in Humans

OBJECTIVE:--The alpha(2)-Heremans-Schmid glycoprotein (AHSG; fetuin-A in animals) impairs insulin signaling in vitro and in rodents. Whether AHSG is associated with insulin resistance in humans is under investigation. In an animal model of diet-induced obesity that is commonly associated with hepati...

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Veröffentlicht in:	Diabetes care 2006-04, Vol.29 (4), p.853-857
Hauptverfasser:	Stefan, Norbert, Hennige, Anita M, Staiger, Harald, Machann, Jürgen, Schick, Fritz, Kröber, Stefan M, Machicao, Fausto, Fritsche, Andreas, Häring, Hans-Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	blood lipids diet-related diseases fatty liver glucose tolerance glycoproteins humans hyperinsulinemia insulin resistance liver longitudinal studies noninsulin-dependent diabetes mellitus nutrition-genotype interaction obesity-related diseases signal transduction
Online-Zugang:	Volltext
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