Selective Loss of Fine Tuning of G[subscript q/11] Signaling by RGS2 Protein Exacerbates Cardiomyocyte Hypertrophy

Alterations in cardiac G protein-mediated signaling, most prominently G[subscript q/11] signaling, are centrally involved in hypertrophy and heart failure development. Several RGS proteins that can act as negative regulators of G protein signaling are expressed in the heart, but their functional rol...

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Veröffentlicht in:	The Journal of biological chemistry 2006-03, Vol.281 (9), p.5811-5820
Hauptverfasser:	Zhang, Wei, Anger, Thomas, Su, Jialin, Hao, Jianming, Xu, Xiaomei, Zhu, Ming, Gach, Agnieszka, Cui, Lei, Liao, Ronglih, Mende, Ulrike
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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